You hold the tablet, and your dog backs away or clamps their mouth shut. If they growl or snap, stop trying to force it and keep your hands safe. Medication may still be important, so call the prescribing veterinary clinic rather than skipping doses or improvising. Ask whether the medicine can be given with food, compounded into another form, or administered at the clinic. Some tablets cannot be crushed or mixed, and some foods are unsafe for dogs, get guidance for this exact prescription.
If your dog seems painful around the mouth, has trouble swallowing, or the refusal is new, tell the veterinarian. A dog who has bitten during handling needs a tailored safety plan, not a stronger grip.
Practice cooperation when no dose is due
At an easy time, teach your dog to approach your hand voluntarily and accept a small food reward. Separately build brief, comfortable touches around the muzzle, stopping before they pull away. The goal is a dog who can choose to participate, not one held still until the tablet is swallowed. Use the clinic's instructions for the medicine itself and never test a bitter pill repeatedly as a training object.
Keep a record of missed or partially swallowed doses and tell the clinic. Do not give a second tablet because you think the first one was spat out unless the veterinary team confirms what to do. Getting the treatment right and keeping trust intact are both part of care.
Sources: Dogs Trust: How to give your dog tablets. Dogs Trust: How to handle your dog.