Short answer: the evidence is mixed and limited, and these products do not replace training. Talk to your vet before giving your dog any supplement.
VCA lists some calming products, such as supplements with L-theanine, which it says may have a calming effect based on initial studies, and synthetic pheromones sold as diffusers, sprays or collars. It also lists Bach flower remedies and a probiotic diet. It describes them as options to discuss with a vet, not as cures.
The AKC explains that calming diffusers and sprays work by copying certain scents, such as the mother dog's, and notes that this is a fairly new area.
Fear and anxiety respond best to a plan: a vet check, management and gradual training. See a safe space for fireworks and the reactive dog threshold.
Do not give any supplement or product without asking your vet first, especially if your dog takes medicine.
This article is general education, not veterinary advice. If your dog seems unwell, is in pain, or something changed suddenly, call your vet. If it could be an emergency, do not wait.
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This guide does not cover medical care. It is background on clear, calm handling at home.
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